Research



Basic Research

Basic Research

* Research animal models for neurodevelopmental risk genes * Advance our understanding of how major Autism Spectrum Disorder (ASD) risk...

Drug Discovery

Drug Discovery

* Screening for drug candidates that regulate neurodevelopmental gene expression * Optimize procedures and workflows to determine the limit of...

Funding

Funding

Our lab operates thanks to Scripps funds, the generosity of donors, fundations and NIH grants. ### Fundations * SRF -...

Our research program is rapidaly expanding towards exciting new horizons in basic and translational research.

The Rumbaugh laboratory is devoted to the understanding of how synapse and circuit mechanisms contribute to cognition and behavioral adaptions. In particular, we are interested in how major neurodevelopmental risk genes (i.e. genes that when mutated cause a defined neurodevelopmental disorder) disrupt synapse function and circuit connectivity. Our approach is to applying cutting edge technology to the study of synapse and circuit function both in vitro and in vivo to determine how major risk genes disrupt behavior and adaptive functions associated with neurodevelopmental disorders.

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